Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.57 |
| ▸ | TNF | P01375 | 3/20 | 0.55 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689466 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL22636828 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL18708299 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL22636832 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL22636830 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL18689465 | 1.00 | TLR2 (0.57) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL27252657 | 0.93 | TLR2 (0.49) | TLR2TNFSLC17A5KMT2A | |
| SCHEMBL31682400 | 0.93 | SLC17A5 (0.53) | TLR2TNFSLC17A5MDM4TP53 | |
| SCHEMBL20547534 | 0.91 | TNF (0.48) | TLR2TNFSLC17A5KMT2AMDM4 | |
| SCHEMBL10073558 | 0.90 | TLR2 (0.59) | TLR2TNFSLC17A5KMT2AMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225781-A1 | PEPTIDE CONJUGATE AMYLIN AGONISTS AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2020-11-12 | — | — | WO | disclosed |