Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783520 | 1.00 | MAPK1 (0.34) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL29783516 | 1.00 | MAPK1 (0.34) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL80486 | 0.89 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3117730 | 0.89 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL977522 | 0.89 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL22637997 | 0.89 | MAPK1 (0.35) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3608660 | 0.87 | MAPK1 (0.37) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL29783525 | 0.87 | MAPK1 (0.37) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL79687 | 0.87 | MAPK1 (0.37) | MAPK1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL975954 | 0.87 | MAPK1 (0.38) | MAPK1KMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227491-A1 | DEUTERATED TRIAZOLOPYRIMIDINES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-11-12 | — | — | WO | disclosed |