Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.73 |
| ▸ | GSK3B | P49841 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598038 | 1.00 | USP2 (1.00) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL13598037 | 0.99 | USP2 (0.98) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL13598042 | 0.86 | USP2 (0.76) | USP2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13598043 | 0.84 | USP2 (0.73) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL15966789 | 0.82 | GSK3B (1.00) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL12870003 | 0.82 | GSK3B (1.00) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL13598044 | 0.81 | KDM4E (0.70) | USP2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13598056 | 0.81 | GSK3B (0.98) | USP2KDM4EGSK3BALDH1A1HPGD | |
| SCHEMBL13598035 | 0.80 | KMT2A (1.00) | USP2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6121034 | 0.80 | USP2 (0.66) | USP2KDM4EGSK3BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | USP2 3312/4885KDM4E 4343/4885GSK3B 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.