SCHEMBL226428

SCHEMBL226428

[CH2]CC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10456308 0.90
SCHEMBL717510 0.90
SCHEMBL7588349 0.90
SCHEMBL2198370 0.88
SCHEMBL4673878 0.87
SCHEMBL373432 0.87
SCHEMBL3617414 0.81
SCHEMBL373571 0.77
SCHEMBL373287 0.77
SCHEMBL12737502 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 783 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3635450-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-05-08 EP claimed
EP-3481876-B9 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF JOHNSON & JOHNSON VISION CARE (US) 2023-12-13 EP claimed
US-20230364832-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-16 US claimed
US-20230350100-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 US claimed
WO-2023209631-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-02 WO claimed
WO-2023209630-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
EP-3481876-B1 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF JOHNSON & JOHNSON VISION CARE (US) 2023-09-27 EP claimed
EP-4235274-A2 SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2023-08-30 EP claimed
EP-3928967-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-26 EP claimed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP claimed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP claimed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP claimed
US-5194542-A Crosslinked Fluoroacrylate Copolymer HOYA CORPORATION (JP) 1993-03-16 US claimed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
EP-0446372-A1 CONTACT LENS HOYA CORPORATION (JP) 1991-09-18 EP claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed
US-4933406-A OXYGEN-PERMEABLE, RIGID NIPPON OIL AND FATS CO., LTD. (JP) 1990-06-12 US claimed
EP-0114894-B1 OXYGEN-PERMEABLE HARD CONTACT LENS HOYA CORPORATION (JP) 1988-01-27 EP claimed
US-4481049-A UNSATURATED ESTER CONTAINING SILICON AT&T BELL LABORATORIES (US) 1984-11-06 US claimed