Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 17/20 | 0.41 |
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16064342 | 1.00 | CTSC (0.41) | CTSCCTSKPREPALDH1A1 | |
| SCHEMBL16064313 | 0.90 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL16064323 | 0.90 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL22642902 | 0.90 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL22642845 | 0.89 | CTSC (0.43) | CTSCCTSKPREP | |
| SCHEMBL16064430 | 0.89 | CTSC (0.43) | CTSCCTSKPREP | |
| SCHEMBL19186928 | 0.87 | CTSC (0.44) | CTSCCTSKPREP | |
| SCHEMBL15081605 | 0.87 | CTSC (0.44) | CTSCCTSKPREP | |
| SCHEMBL22643310 | 0.85 | CTSC (0.47) | CTSCCTSKPREP | |
| SCHEMBL16064315 | 0.85 | CTSC (0.47) | CTSCCTSKPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970283-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2020-11-11 | — | — | EP | disclosed |