Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 15/20 | 0.49 |
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16064223 | 0.89 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL22642850 | 0.85 | CTSC (0.51) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22643077 | 0.84 | CTSC (0.48) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22642801 | 0.84 | CTSC (0.48) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22643251 | 0.84 | CTSC (0.47) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22642810 | 0.83 | PREP (0.39) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22642792 | 0.83 | CTSC (0.49) | CTSCCTSKPREPDPP4 | |
| SCHEMBL26079728 | 0.83 | PREP (0.43) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22643115 | 0.83 | CTSC (0.45) | CTSCCTSKPREPDPP4 | |
| SCHEMBL22643244 | 0.82 | CTSC (0.51) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970283-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2020-11-11 | — | — | EP | disclosed |