Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22644209 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644207 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL29466880 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644215 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644211 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644212 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644206 | 1.00 | S1PR1 (0.38) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644210 | 0.99 | S1PR1 (0.36) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644219 | 0.96 | S1PR1 (0.35) | S1PR1S1PR2S1PR3LPAR2NPC1 | |
| SCHEMBL22644197 | 0.95 | S1PR2 (0.34) | S1PR1S1PR2S1PR3LPAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966871-B1 | DIAMONDOID COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |
| US-20220209150-A1 | DIAMONDOID COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
| WO-2020225270-A1 | DIAMONDOID COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220209150-A1 | DIAMONDOID COMPOUNDS | CCND2, ZYX, CCNB2 | S1PR1 80/4885S1PR2 71/4885S1PR3 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.