SCHEMBL22646380

SCHEMBL22646380

Cc1c(S(=O)(=O)NC(C)C(F)(F)F)c2n(c1C(=O)Nc1ccc(F)c(C#N)c1)CCC2

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22646456 0.98 SLC10A1 (0.53) SLC10A1
SCHEMBL22646306 0.97 SLC10A1 (0.52) SLC10A1
SCHEMBL21869097 0.93 SLC10A1 (0.57) SLC10A1
SCHEMBL22646286 0.91 SLC10A1 (0.51) SLC10A1
SCHEMBL21869517 0.91 SLC10A1 (0.51) SLC10A1
SCHEMBL22646316 0.90 SLC10A1 (0.57) SLC10A1
SCHEMBL22646298 0.89 SLC10A1 (0.50) SLC10A1
SCHEMBL21869115 0.89 SLC10A1 (0.54) SLC10A1
SCHEMBL22646484 0.88 SLC10A1 (0.49) SLC10A1
SCHEMBL22646354 0.88 SLC10A1 (0.57) SLC10A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591334-B2 Substituted pyrrolizines for the treatment of hepatitis B SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) 2023-02-28 US disclosed
US-20200354366-A1 BICYCLIC NUCLEOCAPSID INHIBITOR AND USE OF SAME AS DRUG IN TREATMENT OF HEPATITIS B SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) 2020-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591334-B2 Substituted pyrrolizines for the treatment of hepatitis B SLC10A1, NUP188, NR1H4 SLC10A1 1/4885
US-20200354366-A1 BICYCLIC NUCLEOCAPSID INHIBITOR AND USE OF SAME AS DRUG IN TREATMENT OF HEPATITIS B SLC10A1, NR1H4, NUP188 SLC10A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.