Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.72 |
| ▸ | NAALAD2 | Q9Y3Q0 | 7/20 | 0.72 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.72 |
| ▸ | GRN | P28799 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974626 | 0.89 | FOLH1 (0.66) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19918397 | 0.87 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL10089708 | 0.85 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102890 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18161468 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL12145776 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102870 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1377049 | 0.85 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL22054657 | 0.83 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL22054340 | 0.83 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014992-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | YALE UNIVERSITY (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200354476-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | UNIV YALE (US) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354476-A1 | CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS | BRDT, PAICS, KLK3 | FOLH1 56/4885NAALAD2 2674/4885RIMKLA 3306/4885 |
| US-11014992-B2 | Chimeric small molecules for the recruitment of antibodies to cancer cells | BRDT, PAICS, KLK3 | FOLH1 56/4885NAALAD2 2674/4885RIMKLA 3306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.