Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 8/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22646866 | 0.89 | NTRK1 (0.59) | NTRK1NTRK3NTRK2 | |
| SCHEMBL27060302 | 0.88 | NTRK1 (0.49) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24295456 | 0.85 | NTRK1 (0.49) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22646860 | 0.84 | NTRK1 (0.43) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22646875 | 0.84 | NTRK1 (0.49) | NTRK1NTRK3NTRK2 | |
| SCHEMBL27060140 | 0.84 | NTRK1 (0.45) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22646840 | 0.84 | NTRK1 (0.43) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24295155 | 0.83 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL27060235 | 0.83 | NTRK1 (0.43) | NTRK1NTRK3NTRK2 | |
| SCHEMBL27060206 | 0.83 | NTRK1 (0.50) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3967696-A1 | COMPOUND USED AS KINASE INHIBITOR AND APPLICATION THEREOF | TYK Medicines Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020224626-A1 | COMPOUND USED AS KINASE INHIBITOR AND APPLICATION THEREOF | 浙江同源康医药股份有限公司 | 2020-11-12 | — | — | WO | disclosed |