Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.71 |
| ▸ | JAK2 | O60674 | 11/20 | 0.70 |
| ▸ | TYK2 | P29597 | 8/20 | 0.69 |
| ▸ | JAK3 | P52333 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22696706 | 0.86 | JAK1 (0.75) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22696571 | 0.85 | JAK1 (0.82) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648770 | 0.83 | JAK1 (1.00) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648749 | 0.82 | JAK1 (1.00) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22638037 | 0.81 | JAK1 (0.76) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648754 | 0.81 | JAK1 (1.00) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL29467004 | 0.81 | JAK1 (0.76) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648764 | 0.81 | JAK1 (0.75) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648746 | 0.81 | JAK1 (0.77) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL22648892 | 0.81 | JAK1 (1.00) | JAK1JAK2TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227563-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |