SCHEMBL22650684

SCHEMBL22650684

Clc1ccc(-c2ccc3c(c2)sc2ccc4ccccc4c23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.47
CYP1A1 P04798 5/20 0.47
CYP1B1 Q16678 5/20 0.47
PTGES O14684 1/20 0.41
KDM4E B2RXH2 2/20 0.39
F9 P00740 2/20 0.35
NQO2 P16083 2/20 0.35
NQO1 P15559 1/20 0.35
MCL1 Q07820 1/20 0.34
CYP2A6 P11509 1/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22174350 0.88 KDM4E (0.46) CYP1A2CYP1A1CYP1B1KDM4ENQO2
SCHEMBL31364126 0.88 KDM4E (0.46) CYP1A2CYP1A1CYP1B1KDM4ENQO2
SCHEMBL18803777 0.85 CYP1A1 (0.39) CYP1A2CYP1A1CYP1B1F9NQO2
SCHEMBL21190454 0.85 NQO2 (0.40) CYP1A2CYP1A1CYP1B1F9NQO2
SCHEMBL17932942 0.84 F9 (0.40) CYP1A2CYP1A1CYP1B1PTGESKDM4E
SCHEMBL18267024 0.84 F9 (0.40) CYP1A2CYP1A1CYP1B1PTGESKDM4E
SCHEMBL10122713 0.83 NQO2 (0.41) CYP1A2CYP1A1CYP1B1NQO2NQO1
SCHEMBL21190614 0.82 CYP1A2 (0.44) CYP1A2CYP1A1CYP1B1F9NQO2
SCHEMBL17382968 0.82 MCL1 (0.37) CYP1A2CYP1A1CYP1B1F9NQO2
SCHEMBL17944275 0.82 F9 (0.42) CYP1A2CYP1A1CYP1B1F9NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 WO disclosed