Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15901561 | 0.99 | BRD4 (0.42) | BRD4KDM4EMEN1USP2MAPT | |
| SCHEMBL15901081 | 0.92 | BRD4 (0.48) | BRD4KDM4EMEN1USP2MAPT | |
| SCHEMBL15908088 | 0.82 | KDM4E (0.37) | KDM4EMEN1USP2MAPTIDO1 | |
| SCHEMBL16476439 | 0.81 | KDM4E (0.42) | KDM4EMEN1USP2MAPTIDO1 | |
| Bromide SCHEMBL17254518 | 0.80 | KDM4E (0.42) | KDM4EMEN1USP2MAPTIDO1 | |
| SCHEMBL15908087 | 0.78 | KDM4E (0.40) | KDM4EMEN1USP2MAPTIDO1 | |
| SCHEMBL15908095 | 0.77 | KDM4E (0.43) | KDM4EMEN1USP2MAPTIDO1 | |
| SCHEMBL19405681 | 0.77 | MEN1 (0.65) | BRD4KDM4EMEN1USP2MAPT | |
| SCHEMBL15908041 | 0.76 | MEN1 (0.43) | KDM4EMEN1USP2MAPTIDO1 | |
| SCHEMBL15908133 | 0.76 | CYP1A2 (0.40) | KDM4EMEN1USP2MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838902-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE OF SAME | TriOptoTec GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-2723742-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |