Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342407 | 0.80 | KDM4E (0.44) | KDM4EGPR3MAPTGAAHTT | |
| SCHEMBL29598792 | 0.80 | KDM4E (0.57) | KDM4EGPR3MAPTGAAHTT | |
| SCHEMBL241588 | 0.80 | KDM4E (0.57) | KDM4EGPR3MAPTGAAHTT | |
| SCHEMBL159416 | 0.79 | KDM4E (0.59) | KDM4EGPR3MAPTLMNAMEN1 | |
| SCHEMBL31684807 | 0.79 | KDM4E (0.59) | KDM4EGPR3MAPTLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL28873693 | 0.79 | KDM4E (0.55) | KDM4EGPR3PTPN22MAPTGAA | |
| SCHEMBL8758380 | 0.78 | KDM4E (0.46) | KDM4EGPR3PTPN22MAPTGAA | |
| Hydrochloric Acid SCHEMBL9110426 | 0.77 | KDM4E (0.57) | KDM4EGPR3PTPN22MAPTLMNA | |
| SCHEMBL28342409 | 0.75 | KDM4E (0.50) | KDM4EGPR3MAPTGAAMEN1 | |
| SCHEMBL5379235 | 0.74 | KDM4E (0.48) | KDM4EGPR3MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737369-A1 | ANTI-AGING AND SKIN TONE LIGHTENING COMPOSITIONS AND METHODS FOR SAME | Truetiva Inc. (US) | 2020-11-18 | — | — | EP | disclosed |