SCHEMBL2265485

SCHEMBL2265485

CC(C)NCc1ccc(CC(N)C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 6/20 0.59
▸ PTGS1 P23219 3/20 0.58
▸ ALPI P09923 1/20 0.58
▸ PKM P14618 1/20 0.58
▸ XIAP P98170 1/20 0.58
▸ HIF1A Q16665 4/20 0.51
▸ CYP3A4 P08684 3/20 0.51
▸ ALOX15 P16050 3/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ TDP1 Q9NUW8 2/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ ABCB11 O95342 1/20 0.51
▸ CHRM2 P08172 1/20 0.51
▸ ADRA2A P08913 1/20 0.51
▸ CHRM1 P11229 1/20 0.51
▸ ACHE P22303 1/20 0.51
▸ OPRM1 P35372 1/20 0.51
▸ DRD3 P35462 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1822471 1.00 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL12611747 0.83 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL16577961 0.83 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.82 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL5608012 0.81 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL5608007 0.81 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL8237191 0.81 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL12611746 0.81 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL14233567 0.80 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL4624973 0.80 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 — — EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 — — US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 — — US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 — — US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 — — EP disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 — — WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 — — US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 — — EP disclosed
US-8445440-B2 Dimeric IAP inhibitors NOVARTIS AG (CH) 2013-05-21 — — US disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 — — EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 — — EP disclosed
WO-2011104266-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-09-01 — — WO disclosed
US-20110206690-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-08-25 — — US disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 — — EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 — — WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 — — US disclosed
US-7192570-B2 Compositions of somatostatin analogues UNIVERSITY OF BERN (CH) 2007-03-20 — — US disclosed
US-7192570-B2 Compositions of somatostatin analogues UNIVERSITY OF BERN (CH) 2007-03-20 — — US disclosed
EP-1283216-A1 Somatostatin analogues binding to all somatostatin receptor subtypes and their use Mallinckrodt Inc. (US) 2003-02-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110206690-A1 DIMERIC IAP INHIBITORS XIAP, BIRC5, BIRC2 SLC7A5 3081/4885PTGS1 3021/4885ALPI 2153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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