Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 19/20 | 1.00 |
| ▸ | PLK1 | P53350 | 1/20 | 0.85 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517373 | 1.00 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL22658498 | 0.95 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL29767861 | 0.92 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL29517224 | 0.92 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL22658775 | 0.89 | PTK2 (0.94) | PTK2PLK1LRRK2 | |
| SCHEMBL29517311 | 0.89 | PTK2 (0.94) | PTK2PLK1LRRK2 | |
| SCHEMBL29767867 | 0.89 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL29517755 | 0.86 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 | |
| SCHEMBL29517325 | 0.85 | PTK2 (1.00) | PTK2PLK1 | |
| SCHEMBL29517502 | 0.83 | PTK2 (1.00) | PTK2PLK1MAPK7LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020231726-A1 | SMALL-MOLECULE FOCAL ADHESION KINASE (FAK) INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-19 | — | — | WO | disclosed |