Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.50 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664894 | 1.00 | GSK3B (0.50) | GSK3BBTKPIK3C3MAPK8MAPK10 | |
| SCHEMBL29533042 | 1.00 | GSK3B (0.50) | GSK3BBTKPIK3C3MAPK8MAPK10 | |
| SCHEMBL29766552 | 0.87 | BTK (0.45) | BTK | |
| SCHEMBL20683040 | 0.87 | BTK (0.45) | BTK | |
| SCHEMBL26073278 | 0.86 | BTK (0.43) | GSK3BBTK | |
| SCHEMBL22659435 | 0.85 | GSK3B (0.56) | GSK3BBTKPIK3C3 | |
| SCHEMBL22659437 | 0.85 | GSK3B (0.56) | GSK3BBTKPIK3C3 | |
| SCHEMBL29766356 | 0.83 | BTK (0.69) | BTK | |
| SCHEMBL20683053 | 0.83 | BTK (0.69) | BTK | |
| SCHEMBL16814090 | 0.80 | BTK (0.49) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232330-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2020-11-19 | — | — | WO | disclosed |