Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.74 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.74 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.74 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | AHCY | P23526 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21118446 | 0.91 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22666442 | 0.89 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22020877 | 0.88 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL20253540 | 0.87 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21372144 | 0.86 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5021593 | 0.83 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL23692926 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL26639075 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL25768221 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21090693 | 0.81 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812370-A1 | ASYMMETRIC AUXILIARY GROUP | Wave Life Sciences Ltd. (SG) | 2021-04-28 | — | — | EP | disclosed |
| EP-2872485-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2020-12-16 | — | — | EP | disclosed |
| US-20200362337-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-11-19 | — | — | US | disclosed |