Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | FDPS | P14324 | 9/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767799 | 0.85 | SMPD1 (0.33) | SMPD1GGPS1 | |
| SCHEMBL22666306 | 0.75 | — | — | |
| SCHEMBL7859704 | 0.69 | SMPD1 (0.50) | SMPD1GGPS1FDPSLPAR1LPAR3 | |
| SCHEMBL23692666 | 0.68 | S1PR4 (0.32) | — | |
| SCHEMBL19928210 | 0.68 | S1PR4 (0.32) | — | |
| SCHEMBL20066540 | 0.68 | S1PR4 (0.32) | — | |
| SCHEMBL25979519 | 0.68 | CNR2 (0.36) | — | |
| SCHEMBL18430459 | 0.68 | SMPD1 (0.35) | SMPD1GGPS1FDPS | |
| SCHEMBL7859706 | 0.67 | SMPD1 (0.67) | SMPD1GGPS1FDPSLPAR1LPAR3 | |
| SCHEMBL22403876 | 0.67 | SMPD1 (0.67) | SMPD1GGPS1FDPSLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200362337-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-11-19 | — | — | US | disclosed |