Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19187344 | 0.89 | TRPV1 (0.35) | MALT1NPY5RTRPV1 | |
| SCHEMBL22667955 | 0.88 | PHGDH (0.33) | NPY5RTRPV1 | |
| SCHEMBL15218531 | 0.84 | CNR2 (0.39) | MALT1NPY5RTRPV1CNR2 | |
| SCHEMBL19187411 | 0.83 | MALT1 (0.34) | MALT1NPY5RCYP3A4CYP3A5TRPV1 | |
| SCHEMBL19188250 | 0.76 | KDR (0.36) | MALT1NPY5RTRPV1NTRK1 | |
| SCHEMBL15218534 | 0.72 | POLB (0.48) | NPY5R | |
| SCHEMBL15218533 | 0.72 | IDO1 (0.39) | MALT1NPY5RTRPV1CNR2 | |
| SCHEMBL22667948 | 0.71 | TRPV1 (0.36) | MALT1NPY5RTRPV1 | |
| SCHEMBL22536978 | 0.69 | MAPT (0.38) | CYP3A4CYP3A5TRPV1 | |
| SCHEMBL15209370 | 0.67 | CLK1 (0.42) | MALT1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738958-A1 | AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES AS CCR(9) ANTAGONISTS | ChemoCentryx, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |