Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22669096 | 0.86 | HRH3 (0.49) | HRH3TAAR1 | |
| SCHEMBL22669017 | 0.86 | HRH3 (0.49) | HRH3 | |
| SCHEMBL22668920 | 0.84 | HRH3 (0.68) | HRH3 | |
| SCHEMBL4513431 | 0.82 | GBA1 (0.52) | HRH3ACHEGBA1 | |
| SCHEMBL14660575 | 0.82 | GBA1 (0.52) | HRH3ACHEGBA1 | |
| SCHEMBL22668719 | 0.82 | GBA1 (0.52) | HRH3ACHEGBA1 | |
| SCHEMBL22668852 | 0.81 | HRH3 (0.44) | HRH3 | |
| SCHEMBL22668922 | 0.79 | HRH3 (0.42) | HRH3 | |
| SCHEMBL22668928 | 0.79 | HRH3 (0.41) | HRH3TAAR1 | |
| SCHEMBL22668731 | 0.78 | HRH3 (0.53) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020229968-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2020-11-19 | — | — | WO | disclosed |