⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643365 | 0.74 | — | — | |
| SCHEMBL22679880 | 0.70 | — | — | |
| SCHEMBL18879294 | 0.70 | — | — | |
| SCHEMBL18744005 | 0.70 | — | — | |
| SCHEMBL24485532 | 0.70 | — | — | |
| SCHEMBL9928516 | 0.68 | — | — | |
| SCHEMBL22664724 | 0.67 | — | — | |
| SCHEMBL13624519 | 0.67 | — | — | |
| SCHEMBL24603124 | 0.67 | — | — | |
| SCHEMBL12687233 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |
| US-20240067627-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS AG (CH) | 2024-02-29 | — | — | US | disclosed |
| US-11254653-B2 | NLRP3 inflammasome inhibitors | NOVARTIS AG (CH) | 2022-02-22 | — | — | US | disclosed |
| US-20200361899-A1 | NLRP3 INFLAMMASOME INHIBITORS | NOVARTIS PHARMA AG (CH) | 2020-11-19 | — | — | US | disclosed |