SCHEMBL22672134

SCHEMBL22672134

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6-c6ccccc6)cc54)c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PDE10A Q9Y233 1/20 0.34
PTGER4 P35408 1/20 0.34
GAA P10253 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPY5R Q15761 1/20 0.32
MAPK14 Q16539 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSPO P30536 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ABCG2 Q9UNQ0 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22672103 0.97 ATM (0.40) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL19862588 0.93 KDM4E (0.39) KDM4EATML3MBTL1PDE10AGAA
SCHEMBL21965149 0.93 KDM4E (0.39) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL17714741 0.92 KDM4E (0.36) KDM4EATML3MBTL1PTGER4MEN1
SCHEMBL22010677 0.92 KDM4E (0.40) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL21147803 0.92 KDM4E (0.44) KDM4EATML3MBTL1PDE10AGAA
SCHEMBL23510060 0.91 KDM4E (0.38) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL23510058 0.91 KDM4E (0.40) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL22672217 0.91 KDM4E (0.40) KDM4EATML3MBTL1PDE10APTGER4
SCHEMBL14748986 0.91 KDM4E (0.37) KDM4EATML3MBTL1PTGER4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200365811-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTRONIC DEVICE, COMPOSITION, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND COMPOSITION FILM IDEMITSU KOSAN CO.,LTD. (JP) 2020-11-19 US disclosed