SCHEMBL2267485

SCHEMBL2267485

CCNCCC[SiH2]C=CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.42
CYP2C19 P33261 2/20 0.39
MEN1 O00255 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
SAT1 P21673 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275327 0.80 HTR2A (0.31)
SCHEMBL2270078 0.71
SCHEMBL25041835 0.68 KDM1A (0.45) KDM1ACYP2C19MEN1GLAKMT2A
SCHEMBL22212019 0.67 KDM1A (0.57) KDM1ACYP2C19MEN1GLAKMT2A
SCHEMBL28300574 0.67
SCHEMBL3912322 0.64 CYP2C19 (0.42) KDM1ACYP2C19MEN1GLAKMT2A
SCHEMBL2101998 0.63
SCHEMBL2100369 0.63 CYP2C19 (0.36) KDM1ACYP2C19MEN1GLAKMT2A
SCHEMBL331175 0.62 CYP2C19 (0.86) KDM1ACYP2C19MEN1GLAKMT2A
SCHEMBL330921 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed