Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22675491 | 0.91 | MEN1 (0.37) | IRAK4KCNA5 | |
| SCHEMBL22675483 | 0.90 | PARP1 (0.40) | IRAK4IRAK1KCNA5 | |
| SCHEMBL22675479 | 0.79 | CD274 (0.48) | — | |
| SCHEMBL29984262 | 0.77 | CD274 (0.46) | — | |
| SCHEMBL31108217 | 0.76 | CD274 (0.46) | — | |
| SCHEMBL23200203 | 0.75 | AAK1 (0.38) | KCNA5 | |
| SCHEMBL38664462 | 0.74 | DDB1 (0.34) | IRAK4IRAK1KCNA5 | |
| SCHEMBL25664268 | 0.74 | DDB1 (0.34) | IRAK4IRAK1KCNA5 | |
| SCHEMBL23604509 | 0.73 | CD274 (0.41) | KCNA5 | |
| SCHEMBL24687471 | 0.73 | DDB1 (0.33) | IRAK4IRAK1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228649-A1 | SUBSTITUTED PHENYLPROPENYLPYRIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |