SCHEMBL2267693

SCHEMBL2267693

CC1(C)CNCCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3990277 1.00 HIF1A (0.36)
Hydrochloric Acid SCHEMBL31309953 0.96 HIF1A (0.33)
SCHEMBL14580318 0.87 CXCR4 (0.53)
SCHEMBL21483242 0.86 CXCR4 (0.41)
SCHEMBL18459769 0.84
SCHEMBL21305079 0.81 HIF1A (0.35)
SCHEMBL6551757 0.81
SCHEMBL15928062 0.80 HIF1A (0.39)
SCHEMBL2010663 0.79
SCHEMBL83077 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556758-B1 1,2-DIHYDRO-1,6-NAPHTHYRIDIN-2-ONE DERIVATIVES AS CDK4/6 INHIBITORS CSTONE PHARMACEUTICALS SUZHOU CO LTD (CN) 2024-07-17 EP disclosed
EP-3919494-A1 JANUS KINASE (JAK) FAMILY INHIBITOR, PREPARATION OF SAME, AND APPLICATIONS THEREOF Jiangsu Vcare Pharmatech Co., Ltd (CN) 2021-12-08 EP disclosed
WO-2021218997-A1 SUBSTITUTED FIVE-MEMBERED AZA-RING COMPOUND AND USE THEREOF IN DRUG 东莞市东阳光新药研发有限公司 2021-11-04 WO disclosed
US-20210276966-A1 Phenyl-Piperazine Derivatives As Serotonin Reuptake Inhibitors H. LUNDBECK A/S (DK) 2021-09-09 US disclosed
WO-2020243457-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF VIOGEN BIOSCIENCES, LLC (US) 2020-12-03 WO disclosed
WO-2019165158-A1 IL-6 INHIBITORS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-08-29 WO disclosed
US-9820488-B2 Compounds for the control of endoparasites ELANCO TIERGESUNDHEIT AG (CH) 2017-11-21 US disclosed
US-20170253568-A1 HOMOPIPERAZINE-BASED CATALYSTS FOR NEUTRALIZATION OF ORGANOPHOSPHORUS-BASED COMPOUNDS U.S. DEPARTMENT OF ENERGY 2017-09-07 US disclosed
US-9580404-B2 Substituted azines as pesticides NOVARTIS TIERGESUNDHEIT AG (US) 2017-02-28 US disclosed
EP-2958918-B1 DIHYDROPTERIDINONES II BOEHRINGER INGELHEIM INT (DE) 2016-12-07 EP disclosed
EP-1785418-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-05-16 EP disclosed
EP-1762568-A1 PYRAZOLE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-03-14 EP disclosed
WO-2007025632-A2 NITROOXY DERIVATIVES OP GLUCOCORTICOIDS NICOX S.A. (FR) 2007-03-08 WO disclosed
WO-2007000642-A1 FLUOROPROSTAGLANDINS NITRODERIVATIVES PFIZER INC. (US) 2007-01-04 WO disclosed
US-20060189591-A1 Five-membered heterocyclic derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-08-24 US disclosed
US-20060128685-A1 Pyrazole derivative DAIICHI PHARMACEUTICAL CO., LTD., (JP) 2006-06-15 US disclosed
EP-1621537-A1 FIVE-MEMBERED HETEROCYCLIC DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-02-01 EP disclosed
EP-1591443-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-02 EP disclosed
WO-2005011646-A2 NITROOXY DERIVATIVES OF LOSARTAN, VALSATAN, CANDESARTAN, TELMISARTAN, EPROSARTAN AND OLMESARTAN AS ANGIOTENSIN-II RECEPTOR BLOCKERS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES NICOX S.A. (FR) 2005-02-10 WO disclosed
WO-2004106300-A1 CAPTOPRIL DERIVATIVES NICOX S.A. (FR) 2004-12-09 WO disclosed