⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284153 | 0.79 | — | — | |
| SCHEMBL9452502 | 0.79 | — | — | |
| SCHEMBL759891 | 0.79 | — | — | |
| SCHEMBL3453979 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2214173 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL15561475 | 0.76 | — | — | |
| SCHEMBL23660524 | 0.72 | — | — | |
| SCHEMBL11490464 | 0.71 | — | — | |
| SCHEMBL23660587 | 0.71 | — | — | |
| SCHEMBL340 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993523-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2015-03-31 | — | — | US | disclosed |
| US-20130309247-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| EP-2651917-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| EP-2651919-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130266590-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2013-10-10 | — | — | US | disclosed |
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012080271-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080260-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
| EP-0980016-B1 | ALIGNING AGENT FOR LIQUID CRYSTAL | NISSAN CHEMICAL IND LTD (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2006056663-A1 | METHOD OF SCREENING COMPOUNDS FOR THE TREATMENT OF DIABETES | LAAKSO MARKKU (FI) | 2006-06-01 | — | — | WO | disclosed |
| US-6274695-B1 | THIN FILM POLYMER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| EP-0980016-A1 | ALIGNING AGENT FOR LIQUID CRYSTAL | Nissan Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |