SCHEMBL22677516

SCHEMBL22677516

CCCCCCCCCC(=O)N[C@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC1=O

nearest known ligand 0.82

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.82
RCOR1 Q9UKL0 2/20 0.82
PSMB5 P28074 17/20 0.48
PSMB2 P49721 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22677537 1.00 KDM1A (0.82) KDM1ARCOR1PSMB5PSMB2
SCHEMBL21474067 0.96 KDM1A (0.80) KDM1ARCOR1PSMB5PSMB2
SCHEMBL21258418 0.95 KDM1A (0.81) KDM1ARCOR1PSMB5PSMB2
Polymyxin B5 SCHEMBL21258460 0.95 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
Polymyxin B3 SCHEMBL21474115 0.95 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
Polymyxin B4 SCHEMBL21476967 0.95 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2
SCHEMBL22677532 0.95 KDM1A (0.73) KDM1ARCOR1PSMB5PSMB2
SCHEMBL22677534 0.95 KDM1A (0.73) KDM1ARCOR1PSMB5PSMB2
SCHEMBL22677517 0.95 KDM1A (0.73) KDM1ARCOR1PSMB5PSMB2
SCHEMBL22677292 0.95 KDM1A (0.73) KDM1ARCOR1PSMB5PSMB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885PSMB5 1250/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885PSMB5 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.