SCHEMBL22677610

SCHEMBL22677610

CC(C)C[C@@H]1NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CCc2ccccc2)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@@H](CCN)NC(=O)c2ccc(Oc3ccccc3)cc2)CCNC1=O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.55
RCOR1 Q9UKL0 2/20 0.55
IDE P14735 1/20 0.38
TERF2 Q15554 7/20 0.38
F2 P00734 1/20 0.38
F11 P03951 1/20 0.38
CPN1 P15169 1/20 0.38
CPB2 Q96IY4 1/20 0.38
CTSK P43235 2/20 0.38
CTSL P07711 1/20 0.38
TPSAB1 Q15661 2/20 0.36
PLK1 P53350 1/20 0.35
PLK3 Q9H4B4 1/20 0.35
PLK2 Q9NYY3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22677609 0.95 KDM1A (0.61) KDM1ARCOR1IDETERF2F2
SCHEMBL22677646 0.95 KDM1A (0.61) KDM1ARCOR1IDETERF2F2
SCHEMBL22677596 0.92 KDM1A (0.54) KDM1ARCOR1TERF2F2F11
SCHEMBL22677636 0.88 KDM1A (0.63) KDM1ARCOR1IDETERF2F2
SCHEMBL22678362 0.88 KDM1A (0.63) KDM1ARCOR1IDETERF2F2
SCHEMBL22677624 0.87 KDM1A (0.59) KDM1ARCOR1IDE
SCHEMBL22677598 0.87 KDM1A (0.59) KDM1ARCOR1IDE
SCHEMBL21474048 0.86 KDM1A (0.77) KDM1ARCOR1IDEF11
SCHEMBL22677622 0.85 KDM1A (0.59) KDM1ARCOR1IDE
SCHEMBL22677568 0.82 KDM1A (0.70) KDM1ARCOR1IDETERF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885IDE 986/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885IDE 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.