SCHEMBL22678340

SCHEMBL22678340

CC(C)CCCC(O)CC(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CCc2ccccc2)NC(=O)[C@H](CCN)NC1=O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.65
RCOR1 Q9UKL0 2/20 0.65
TERF2 Q15554 5/20 0.42
CPB2 Q96IY4 4/20 0.40
F2 P00734 3/20 0.40
F11 P03951 3/20 0.40
CPN1 P15169 3/20 0.40
PSMB5 P28074 4/20 0.37
PSMB2 P49721 2/20 0.37
CPA1 P15085 2/20 0.37
F10 P00742 1/20 0.36
F7 P08709 1/20 0.36
FLT1 P17948 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678343 0.95 KDM1A (0.71) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22677635 0.95 KDM1A (0.62) KDM1ARCOR1TERF2CPB2F2
SCHEMBL24270413 0.94 KDM1A (0.62) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22677578 0.94 KDM1A (0.62) KDM1ARCOR1TERF2CPB2F2
SCHEMBL24270416 0.94 KDM1A (0.73) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22678307 0.93 KDM1A (0.72) KDM1ARCOR1TERF2CPB2F2
Octapeptin A1 SCHEMBL31084524 0.93 KDM1A (0.72) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22677583 0.92 KDM1A (0.65) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22677542 0.92 KDM1A (0.61) KDM1ARCOR1TERF2CPB2F2
SCHEMBL22677670 0.92 KDM1A (0.65) KDM1ARCOR1TERF2CPB2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885TERF2 2918/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885TERF2 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.