SCHEMBL22678352

SCHEMBL22678352

CC(C)C[C@@H]1NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@@H](CCN)NC(=O)c2ccnc(-c3ccccc3)c2)CCNC1=O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.61
RCOR1 Q9UKL0 2/20 0.61
IDE P14735 1/20 0.40
MC4R P32245 3/20 0.38
MC1R Q01726 2/20 0.38
TERF2 Q15554 2/20 0.38
F2 P00734 1/20 0.37
F11 P03951 1/20 0.37
CPN1 P15169 1/20 0.37
CPB2 Q96IY4 1/20 0.37
TPSAB1 Q15661 1/20 0.36
KLK7 P49862 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678374 1.00 KDM1A (0.61) KDM1ARCOR1IDEMC4RMC1R
SCHEMBL22678369 0.95 KDM1A (0.68) KDM1ARCOR1IDEMC4RMC1R
SCHEMBL14241072 0.90 KDM1A (0.66) KDM1ARCOR1F11KLK7
SCHEMBL14240745 0.90 KDM1A (0.66) KDM1ARCOR1F11KLK7
SCHEMBL22677636 0.90 KDM1A (0.63) KDM1ARCOR1IDEMC4RMC1R
SCHEMBL22678362 0.90 KDM1A (0.63) KDM1ARCOR1IDEMC4RMC1R
SCHEMBL14240945 0.89 KDM1A (0.74) KDM1ARCOR1F11
SCHEMBL14226791 0.89 KDM1A (0.74) KDM1ARCOR1F11
SCHEMBL14240951 0.86 KDM1A (0.69) KDM1ARCOR1
SCHEMBL22677646 0.86 KDM1A (0.61) KDM1ARCOR1IDEMC4RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885IDE 986/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD KDM1A 4796/4885RCOR1 4836/4885IDE 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.