Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.47 |
| ▸ | TTR | P02766 | 6/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | EYA2 | O00167 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221837 | 0.88 | CYP2C19 (0.47) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL25815357 | 0.85 | SLC22A12 (0.52) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL24102976 | 0.83 | CYP2C19 (0.46) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL25815944 | 0.81 | SLC22A12 (0.56) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL24221834 | 0.79 | SLC22A12 (0.57) | CYP2C19SLC22A12EYA3CYP2C9MEN1 | |
| SCHEMBL25815931 | 0.78 | CYP2C19 (0.41) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL24103345 | 0.78 | SLC22A12 (0.53) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL22680420 | 0.76 | SLC22A12 (0.51) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL22680544 | 0.76 | SLC22A12 (0.53) | CYP2C19SLC22A12TTRNR1H4EYA3 | |
| SCHEMBL1287909 | 0.75 | CYP2C19 (1.00) | CYP2C19SLC22A12TTRNR1H4EYA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252630-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2020232156-A1 | COMPOUND FOR TREATING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |