SCHEMBL22680968

SCHEMBL22680968

CCCC1CC(C)(C)CCN1c1ccc(C#N)c(Cl)c1C

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 18/20 0.60
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2390614 0.77 AR (0.72) ARCYP2C19
SCHEMBL2391997 0.75 AR (1.00) AR
SCHEMBL2392105 0.73 AR (0.63) ARCYP2C19
SCHEMBL26799918 0.69 AR (0.81) AR
SCHEMBL13114861 0.69 AR (0.52) ARCYP2C19
SCHEMBL22667736 0.66 AR (0.55) AR
SCHEMBL2391553 0.66 AR (1.00) ARCYP2C19
SCHEMBL3568120 0.66 AR (0.52) ARCYP2C19
SCHEMBL18540957 0.66 AR (0.55) ARCYP2C19
SCHEMBL18540953 0.66 AR (0.55) ARCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020232119-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NUVATION BIO INC. (US) 2020-11-19 WO disclosed