Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 19/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112716 | 0.88 | OGA (0.68) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16113250 | 0.86 | OGA (0.73) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16113629 | 0.85 | OGA (0.66) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16112772 | 0.85 | OGA (0.73) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16113559 | 0.84 | OGA (0.80) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16113405 | 0.83 | OGA (0.67) | OGAHTTSMN1; SMN2 | |
| SCHEMBL16112443 | 0.83 | OGA (0.61) | OGAHTTSMN1; SMN2 | |
| SCHEMBL20586821 | 0.82 | OGA (1.00) | OGA | |
| SCHEMBL16113037 | 0.82 | OGA (0.62) | OGAHTTSMN1; SMN2 | |
| SCHEMBL20281543 | 0.81 | OGA (0.59) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3389658-B1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME (US) | 2020-11-25 | — | — | EP | disclosed |