SCHEMBL2268449

SCHEMBL2268449

CCCC[SiH](CCC)NC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271598 0.94 TSHR (0.35) EPHX1TSHRLMNATHRB
SCHEMBL2271166 0.88
SCHEMBL2269624 0.83
SCHEMBL2267659 0.77
SCHEMBL2271159 0.76 TSHR (0.32) TSHRLMNA
SCHEMBL18784875 0.73 TSHR (0.38) EPHX1TSHRLMNATHRB
SCHEMBL2101150 0.71
SCHEMBL2102360 0.69 TSHR (0.37) TSHR
SCHEMBL2268849 0.69 TSHR (0.35) TSHRLMNATHRB
SCHEMBL2268196 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed