⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932457 | 0.81 | UHRF1 (0.54) | — | |
| SCHEMBL12596 | 0.79 | — | — | |
| SCHEMBL31421768 | 0.79 | — | — | |
| SCHEMBL4048883 | 0.77 | — | — | |
| SCHEMBL510182 | 0.77 | — | — | |
| SCHEMBL510181 | 0.77 | — | — | |
| SCHEMBL510744 | 0.77 | — | — | |
| SCHEMBL318009 | 0.77 | — | — | |
| SCHEMBL13725194 | 0.77 | — | — | |
| SCHEMBL1443623 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265456-B1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2020-11-18 | — | — | EP | disclosed |