Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 9/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22688782 | 1.00 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688844 | 1.00 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22695121 | 1.00 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422699 | 1.00 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688845 | 1.00 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422764 | 0.94 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422547 | 0.94 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22695326 | 0.94 | NTRK1 (0.38) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688842 | 0.93 | NTRK1 (0.40) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688694 | 0.93 | NTRK1 (0.40) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233645-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | 浙江海正药业股份有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |