Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.81 |
| ▸ | IGF1R | P08069 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588254 | 1.00 | EGFR (0.83) | EGFRKCNH2IGF1R | |
| SCHEMBL22695155 | 0.95 | EGFR (0.84) | EGFRKCNH2IGF1R | |
| SCHEMBL29588348 | 0.95 | EGFR (0.84) | EGFRKCNH2IGF1R | |
| Bromide SCHEMBL29588563 | 0.95 | EGFR (0.84) | EGFRKCNH2IGF1R | |
| Hydrochloric Acid SCHEMBL29588253 | 0.94 | EGFR (0.83) | EGFRKCNH2IGF1R | |
| SCHEMBL22695277 | 0.93 | EGFR (0.72) | EGFRKCNH2IGF1R | |
| SCHEMBL29588690 | 0.93 | EGFR (0.72) | EGFRKCNH2IGF1R | |
| SCHEMBL19532469 | 0.92 | EGFR (0.87) | EGFRKCNH2IGF1R | |
| Glycine SCHEMBL29588700 | 0.91 | EGFR (0.78) | EGFRKCNH2IGF1R | |
| SCHEMBL30017478 | 0.91 | EGFR (0.78) | EGFRKCNH2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020233669-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020233669-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |