⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26251780 | 0.93 | — | — | |
| SCHEMBL19871862 | 0.89 | — | — | |
| SCHEMBL24012450 | 0.85 | — | — | |
| SCHEMBL20099270 | 0.83 | — | — | |
| SCHEMBL16248511 | 0.82 | DPP4 (0.32) | — | |
| SCHEMBL20099250 | 0.81 | — | — | |
| SCHEMBL23790886 | 0.81 | — | — | |
| SCHEMBL25466905 | 0.80 | — | — | |
| SCHEMBL16692598 | 0.79 | DPP4 (0.30) | — | |
| SCHEMBL17446584 | 0.79 | DPP4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844379-B2 | Conjugated antisense compounds and their use | IONIS PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |