SCHEMBL22692804

SCHEMBL22692804

FC(F)(F)COCCOCCOC1CCCCCC1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
EPHX2 P34913 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22692802 0.98 NPC1 (0.38) NPC1EPHX2
SCHEMBL22692805 0.79 NPC1 (0.40) NPC1
SCHEMBL5872501 0.79 NPC1 (0.40) NPC1
SCHEMBL27888448 0.79 NPC1 (0.48) NPC1EPHX2
SCHEMBL4426666 0.77 NPC1 (0.37) NPC1
SCHEMBL29251115 0.76 NPC1 (0.44) NPC1CYP1A2
SCHEMBL10357183 0.76 NPC1 (0.61) NPC1CYP2C19
SCHEMBL6377426 0.76 NPC1 (0.61) NPC1CYP2C19
SCHEMBL6376493 0.76 NPC1 (0.61) NPC1CYP2C19
SCHEMBL6383859 0.76 NPC1 (0.61) NPC1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10847790-B2 Functionalised electrochemically active material and method of functionalisation NEXEON LIMITED (GB) 2020-11-24 US disclosed