Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 7/20 | 0.68 |
| ▸ | RPTOR | Q8N122 | 7/20 | 0.68 |
| ▸ | MLST8 | Q9BVC4 | 7/20 | 0.68 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141306 | 0.89 | MTOR (0.85) | MTORRPTORMLST8DPP4MEN1 | |
| SCHEMBL20129696 | 0.88 | MTOR (0.59) | MTORRPTORMLST8DRD4NAMPT | |
| SCHEMBL20129694 | 0.85 | MTOR (0.65) | MTORRPTORMLST8DPP4NAMPT | |
| SCHEMBL20133660 | 0.84 | MTOR (0.72) | MTORRPTORMLST8DPP4MEN1 | |
| SCHEMBL20133719 | 0.84 | MTOR (0.73) | MTORRPTORMLST8DRD4DPP4 | |
| SCHEMBL20133540 | 0.84 | MTOR (0.77) | MTORRPTORMLST8DPP4MEN1 | |
| SCHEMBL22186355 | 0.83 | MTOR (0.56) | MTORRPTORMLST8DRD4MEN1 | |
| SCHEMBL20133709 | 0.81 | MTOR (1.00) | MTORRPTORMLST8DPP4TSHR | |
| SCHEMBL20133729 | 0.81 | MTOR (1.00) | MTORRPTORMLST8DPP4TSHR | |
| SCHEMBL22693203 | 0.81 | MTOR (0.60) | MTORRPTORMLST8DPP4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.