Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 5/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360303 | 0.81 | MTOR (0.67) | MTORRPTORMLST8DPP4SYK | |
| SCHEMBL22693195 | 0.80 | MTOR (0.51) | MTORRPTORMLST8 | |
| SCHEMBL21360305 | 0.80 | MTOR (0.62) | MTORRPTORMLST8DPP4 | |
| SCHEMBL22693118 | 0.79 | MTOR (0.56) | MTORRPTORMLST8NOS2ALDH1A1 | |
| SCHEMBL22186853 | 0.78 | MTOR (0.53) | MTORRPTORMLST8DPP4NOS2 | |
| SCHEMBL22693190 | 0.76 | MTOR (0.42) | MTORRPTORMLST8 | |
| SCHEMBL22693232 | 0.75 | MTOR (0.47) | MTORRPTORMLST8ALDH1A1TSHR | |
| SCHEMBL22693176 | 0.75 | MTOR (0.42) | MTORRPTORMLST8 | |
| SCHEMBL22693157 | 0.73 | MTOR (0.49) | MTORRPTORMLST8KDM5ANOS2 | |
| SCHEMBL21360417 | 0.67 | MTOR (0.50) | MTORRPTORMLST8ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.