Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.50 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.50 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.50 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133556 | 0.90 | MTOR (0.61) | MTORRPTORMLST8EEDALDH1A1 | |
| SCHEMBL20133704 | 0.86 | MTOR (0.60) | MTORRPTORMLST8EEDALDH1A1 | |
| SCHEMBL22693201 | 0.85 | MTOR (0.53) | MTORRPTORMLST8MAPTHTT | |
| SCHEMBL20141041 | 0.83 | MTOR (0.62) | MTORRPTORMLST8ALDH1A1MAPT | |
| SCHEMBL21360359 | 0.83 | MTOR (0.71) | MTORRPTORMLST8EEDKMT2A | |
| SCHEMBL20133549 | 0.83 | MTOR (0.64) | MTORRPTORMLST8EEDALDH1A1 | |
| SCHEMBL20133543 | 0.83 | MTOR (0.62) | MTORRPTORMLST8EEDKMT2A | |
| SCHEMBL20133670 | 0.81 | MTOR (0.69) | MTORRPTORMLST8MAPTHTT | |
| SCHEMBL20133661 | 0.81 | MTOR (0.56) | MTORRPTORMLST8LMNAKDM4E | |
| SCHEMBL20140890 | 0.81 | MTOR (0.57) | MTORRPTORMLST8LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.