Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 10/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312852 | 0.92 | S1PR2 (0.80) | S1PR2CYP3A4CYP2C19TSHRKMT2A | |
| SCHEMBL22693599 | 0.91 | S1PR2 (0.57) | S1PR2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3311240 | 0.88 | S1PR2 (0.83) | S1PR2MAPT | |
| SCHEMBL3306628 | 0.87 | S1PR2 (0.71) | S1PR2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL14068491 | 0.86 | S1PR2 (0.71) | S1PR2CYP3A4CYP2C19TSHRKMT2A | |
| SCHEMBL13332602 | 0.86 | S1PR2 (0.79) | S1PR2MAPT | |
| SCHEMBL3310336 | 0.86 | S1PR2 (0.79) | S1PR2MAPT | |
| SCHEMBL22693616 | 0.86 | CYP3A4 (0.65) | S1PR2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL22693559 | 0.86 | S1PR2 (0.84) | S1PR2MAPT | |
| SCHEMBL13361516 | 0.85 | KMT2A (0.72) | S1PR2CYP3A4CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | S1PR2, S1PR1, S1PR3 | S1PR2 1/4885CYP3A4 4591/4885CYP2C19 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.