Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852060 | 0.89 | DPP4 (0.47) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL3522772 | 0.83 | DPP4 (0.48) | DPP4LOXL2DPP8HRH1SLC6A2 | |
| SCHEMBL25532686 | 0.83 | DPP4 (0.48) | DPP4LOXL2DPP8HRH1SLC6A2 | |
| SCHEMBL4629386 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL4629392 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL14785710 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL14643273 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL3741345 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL29154187 | 0.82 | DPP4 (0.44) | DPP4LOXL2DPP8GRM8GRM4 | |
| SCHEMBL5346174 | 0.79 | SLC2A1 (0.47) | DPP4SLC6A2SLC6A4SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020235902-A1 | HETEROCYCLE-FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF | 주식회사 보로노이 (KR) | 2020-11-26 | — | — | WO | disclosed |