Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.50 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | TXK | P42681 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25557491 | 0.95 | FGFR1 (0.47) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL22696341 | 0.84 | KDM4E (0.39) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL22696567 | 0.84 | TNK2 (0.40) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL22696565 | 0.84 | TNK2 (0.40) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL21050871 | 0.82 | FGFR1 (0.69) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL25557498 | 0.81 | TNK2 (0.38) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL25557512 | 0.81 | TNK2 (0.38) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL21050888 | 0.80 | FGFR4 (0.72) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL22352688 | 0.80 | FGFR4 (0.72) | FGFR1FGFR3FGFR2FGFR4TNK2 | |
| SCHEMBL25557486 | 0.80 | KDM4E (0.37) | FGFR1FGFR3FGFR2FGFR4TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174535-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. | 2023-06-08 | — | — | US | disclosed |
| WO-2020236524-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2020-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174535-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | FGFR1, FGFR2, FGFR3 | FGFR1 1/4885FGFR3 3/4885FGFR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.