Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17465804 | 0.96 | MAPT (0.57) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL17466017 | 0.81 | MAPT (0.58) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL17466022 | 0.80 | MAPT (0.65) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL6473523 | 0.78 | ELANE (0.46) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL17465996 | 0.74 | MAPT (0.66) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL19034414 | 0.73 | MAPT (0.48) | MAPTTP53THRBALDH1A1MEN1 | |
| SCHEMBL22697146 | 0.72 | TP53 (0.63) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL10718942 | 0.71 | MAPT (0.62) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL10718939 | 0.71 | MAPT (0.62) | MAPTTP53THRBPOLBTDP1 | |
| SCHEMBL10253178 | 0.70 | MAPT (0.43) | MAPTTP53THRBPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |