SCHEMBL226972

SCHEMBL226972

C1=CC=C2CC=CC=C2C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31412624 1.00
Hydrochloric Acid SCHEMBL3407509 0.98
SCHEMBL28561922 0.98
SCHEMBL10076564 0.90
Phosphoric Acid SCHEMBL28561912 0.88
SCHEMBL27765168 0.85
SCHEMBL1478392 0.85
Fumaric Acid SCHEMBL11627721 0.84 TSHR (0.30)
Fumaric Acid SCHEMBL11524892 0.84 TSHR (0.30)
Fumaric Acid SCHEMBL11627725 0.84 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115050915-A Organic electroluminescent device 长春海谱润斯科技股份有限公司 2022-09-13 CN claimed
CN-115050900-A Organic electroluminescent device 长春海谱润斯科技股份有限公司 2022-09-13 CN claimed
EP-3454944-B1 VOLATILE METABOLITE PROFILES FOR THE DIAGNOSIS AND TREATMENT OF MUCORALES FUNGI BRIGHAM & WOMENS HOSPITAL INC (US) 2022-07-13 EP claimed
US-8604201-B2 Use of cyclovinyl phosphine/copper complexes as arylation catalysts CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-12-10 US claimed
EP-2197889-B1 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS CENTRE NAT RECH SCIENT (FR) 2012-07-18 EP claimed
US-20100298569-A1 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 US claimed
EP-2197889-A2 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2010-06-23 EP claimed
EP-2129219-A1 SUBSTITUTED FUSED-RING COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES Synta Pharmaceuticals Corporation (US) 2009-12-09 EP claimed
WO-2009050394-A2 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2009-04-23 WO claimed
US-20080214542-A1 Arylpiperazine Derivatives and their Use as Selective Dopamine D3 Receptor Ligands BIOPROJET (FR) 2008-09-04 US claimed
WO-2000003979-A1 BENZOCYCLOHEPTENES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS, AND THEIR USE FOR PRODUCING MEDICAMENTS SCHERING AKTIENGESELLSCHAFT (DE) 2000-01-27 WO claimed
US-5952335-A ANTITUMOR AGENTS EISAI CO., LTD. (JP) 1999-09-14 US claimed
EP-0831094-A1 FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES Eisai Co., Ltd. (JP) 1998-03-25 EP claimed
EP-0601249-A1 Benzocycloheptene derivative and process for preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1994-06-15 EP claimed
US-5252589-A Inhibits contraction of urinary bladder TANABE SEIKAYU CO., LTD. (JP) 1993-10-12 US claimed
EP-0354078-B1 DERIVATIVES OF BENZOCYCLOHEPTENE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1993-03-10 EP claimed
US-5079245-A 2-trifluoromethyl-7-substitute-6,7,8,9-tetrahydro-[5H]-benzocycloheptenes ADIR ET COMPAGNIE (FR) 1992-01-07 US claimed
EP-0354078-A2 Derivatives of benzocycloheptene, method for their preparation and pharmaceutical compositions containing same ADIR ET COMPAGNIE (FR) 1990-02-07 EP claimed
US-4154852-A ANTIDEPRESSANTS ROUSSEL UCLAF (FR) 1979-05-15 US claimed
US-4091115-A ANTIDEPRESSANTS ROUSSEL UCLAF (FR) 1978-05-23 US claimed