Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075862 | 0.95 | FFAR4 (0.47) | FFAR4GSTP1SRD5A2CAMKK2NCOA1 | |
| SCHEMBL132012 | 0.89 | BRD4 (0.51) | FFAR4SRD5A2CAMKK2PTGS2BRD4 | |
| SCHEMBL21397927 | 0.88 | GSTP1 (0.48) | FFAR4GSTP1SRD5A2CAMKK2MCL1 | |
| SCHEMBL132900 | 0.84 | SRD5A2 (0.55) | GSTP1SRD5A2MCL1 | |
| SCHEMBL134237 | 0.84 | SRD5A2 (0.59) | GSTP1SRD5A2MCL1 | |
| SCHEMBL12551362 | 0.77 | HPGD (0.46) | FFAR4CAMKK2PTGS2BRD4NCOA1 | |
| SCHEMBL19506965 | 0.77 | FFAR4 (0.46) | FFAR4SRD5A2CAMKK2PTGS2BRD4 | |
| SCHEMBL132895 | 0.75 | AKR1C3 (0.56) | FFAR4SRD5A2MCL1FEN1FFAR1 | |
| SCHEMBL9483097 | 0.75 | NCOA1 (0.62) | FFAR4SRD5A2PTGS2NCOA1NCOA3 | |
| SCHEMBL10711068 | 0.74 | NCOA1 (0.69) | FFAR4GSTP1PTGS2BRD4NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526228-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |