SCHEMBL227005

SCHEMBL227005

CCCCCCC(OC)C(OC)(OC)O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.33
LMNA P02545 1/20 0.32
DNM1 Q05193 2/20 0.31
SMPD1 P17405 3/20 0.31
OPRM1 P35372 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230811 1.00 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL230843 1.00 ZDHHC7 (0.33) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL5839501 0.92 CA1 (0.33)
SCHEMBL27343922 0.88 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL9498255 0.88 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL2166252 0.88 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL9845135 0.84
SCHEMBL227006 0.81 ZDHHC7 (0.35) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL230844 0.81 ZDHHC7 (0.35) ZDHHC7LMNADNM1SMPD1OPRM1
SCHEMBL230812 0.81 ZDHHC7 (0.35) ZDHHC7LMNADNM1SMPD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed